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Sample Collection Process
Sample collection The process of acquiring tissues, fluids, any other sample, or material for laboratory analysis is called the sample collection process. For example, if we want to analyze the protein source, it will be eggs because eggs contain a high amount of protein, which will be our sample of analysis. This involves many things that…
Hoffmann Rearrangement
The reaction in which the conversion of amides to amine with one carbon atom less than the starting material in the presence of Br2 and KOH or alkaline Hypohalite is called Hoffmann rearrangement. This rearrangement was given by Agust Wilhem. Reaction : Mechanism of Hoffman Rearrangement: Step 1: Deprotonation of amide by Base (OH)…
Pinacole-pinacolone rearrangement
An Acid catalyzed rearrangement in which 1,2-diol or pinacole is converted to carbonyl compound is called pinacole- pinacolone rearrangement. Pinacole : 2,3- dimethyl butane-2,3-diol Pinacolone :3,3-dimethyl-2- butanone Reaction of Pinacole-pinacolone rearrangement: Mechanism of pinacole-pinacolone rearrangement: Mechanism of pinacole-pinacolone rearrangement takes place in four steps Step(01): In this step hydroxyl group of pinacole is protonated by…